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US 5,843,716 AGranted
Polynucleotide encoding a proline-rich membrane protein
AssigneeIncyte Pharmaceuticals, Inc.
InventorsJanice Au-Young, Roger Coleman
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AssigneeIncyte Pharmaceuticals, Inc.
InventorsJanice Au-Young, Roger Coleman
Estimating the term…
The present invention provides a human proline-rich membrane protein (PRMP) and polynucleotides which identify and encode PRMP. The invention also provides genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding PRMP and a method for producing PRMP. The invention also provides for agonists, antibodies, or antagonists specifically binding PRMP, and their use, in the prevention and treatment of diseases associated with expression of PRMP. Additionally, the invention provides for the use of antisense molecules to polynucleotides encoding PRMP for the treatment of diseases associated with the expression of PRMP. The invention also provides diagnostic assays which utilize the polynucleotide, or fragments or the complement thereof, and antibodies specifically binding PRMP.
An isolated and purified polynucleotide sequence encoding a polypeptide comprising the amino acid sequence of SEQ ID NO:1.
An isolated and purified polynucleotide sequence comprising SEQ ID NO:2.
Dependencies are inferred from the claim text.