Back to results
US 5,843,665 AGranted
Human pyrophosphatase
AssigneeIncyte Pharmaceuticals, Inc.
InventorsPhillip R. Hawkins, Jennifer L. Hillman
Life of this patent
Estimating the term…
Loading patent…
Loading patent…
AssigneeIncyte Pharmaceuticals, Inc.
InventorsPhillip R. Hawkins, Jennifer L. Hillman
Estimating the term…
The present invention provides a human pyrophosphatase (HPYP) and polynucleotides which identify and encode HPYP. The invention also provides genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding HPYP and a method for producing HPYP. The invention also provides for use of HPYP and agonists, antibodies, or antagonists specifically binding HPYP, in the prevention and treatment of cancer and inflammatory diseases. Additionally, the invention provides for the use of antisense molecules to polynucleotides encoding HPYP for the treatment of diseases associated with the expression of HPYP. The invention also provides diagnostic assays which utilize the polynucleotide, or fragments or the complement thereof, and antibodies specifically binding HPYP.
An isolated and purified polynucleotide sequence encoding a human pyrophosphatase consisting of the amino acid sequence of SEQ ID NO:1.
An isolated and purified polynucleotide sequence consisting of SEQ ID NO:2.
A polynucleotide sequence which is fully complementary to SEQ ID NO:2.
Dependencies are inferred from the claim text.