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US 5,843,661 AGranted
Method for construction universal DNA based molecular turing machine
AssigneeCalifornia Institute of Technology
InventorPaul W. K. Rothemund
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Abstract
This invention discloses a novel method for constructing a Universal DNA based molecular Turing machine. Included in the invention is a method of operating the DNA based Turing machine of this invention.
Claims29
A universal molecular Turing machine comprising:
- a circular DNA molecule, having sites representing information storage of the Turing machine, said DNA molecule including:
- an invariant (Inv) restriction site inside the circular DNA molecule;
- a state restriction site also inside the circular DNA molecule, and adjacent to the Inv restriction site;
- a current symbol, encoded on the circular DNA molecule at a distance from said state restriction site that represents a state of the Turing machine;
- a plurality of intervening nucleotides between the state restriction site and the current symbol;
- a plurality of asymmetric restriction enzymes;
- and
- a plurality of transition oligonucleotides, which sre inserted into said circular DNA molecule as additional symbols to encode changes to said information storage caused by operation of said Turing machine.
5 more elements
A method for operating a molecular Turing machine, comprising the steps of:
- forming a Turing tape from a molecule of DNA;
- conducting an operation on said Turing tape by cutting a current symbol with an asymmetric restriction enzyme in the Turing tape;
- mixing a plurality of transition oligonucleotides with the DNA Turing tape at a location of said cutting, to add a new symbol into the DNA Turing tape;
- and
- after adding said new symbol, removing a previous symbol from the Turing tape.
2 more elements
Dependencies are inferred from the claim text.