Methods for the daignosis, of familial amyotrophic lateral sclerosis
AssigneesMassachusetts Institute of Technology, The General Hospital Corporation
InventorsRobert Brown, H. Robert Horvitz, Daniel R. Rosen
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Abstract
Disclosed is the family of genes responsible for the neurodegenerative diseases, particularly Amyotrophic Lateral Sclerosis. Methods and compounds for the diagnosis, prevention, and therapy of the disease are also disclosed.
Claims23
A method of diagnosing an increased likelihood of developing familial ALS in a patient, said method comprising analyzing the DNA of said patient to determine whether said DNA contains a mutation in a SOD 1 gene, such a mutation being an indication that said patient has an increased likelihood of developing familial ALS.
A method of diagnosing a fetus with an increased likelihood of developing familial ALS, said method comprising analyzing the DNA of said fetus to determine whether said DNA contains a mutation in a SOD1 coding sequence, such a mutation being an indication that said fetus has an increased likelihood of developing familial ALS.
Dependencies are inferred from the claim text.