Lubricants for use in tabletting
AssigneeBayer Aktiengesellschaft
InventorThomas A. Alexander
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Abstract
The invention provides a new water soluble lubricant combination which facilitates the production of tablets. The combination of glyceryl behenate and fumaric acid is useful as a lubricant, particularly in tablet compositions containing ingredients where rapid dissolution in an aqueous environment is desired for activity or desired for aesthetic purposes. This lubricant combination has fewer limitations and improved functionality in comparison to standard lubricants presently known. In addition, the lubricants provided may be used with known hydrophobic lubricants to decrease the amount of the hydrophobic lubricant required for lubrication.
Claims8
A method of preparing a tablet, comprising the steps of:
- a. preparing the lubricant combination of glyceryl behenate and micronized fumaric acid;
- b. adding the lubricant combination and the desired tablet ingredients to a mixer;
- c. blending the contents of the mixer;
- d. compressing the blended contents to produce a tablet.
Dependencies are inferred from the claim text.