Lipid soluble forms of thiamine for prevention and treatment of age-related cognitive impairment of the nervous system
OwnerWilliam J. McEnteeinventor
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Abstract
A method for preventing, ameliorating, and/or treating memory and other cognitive disorders associated with aging, such as Age-Associated Memory Impairment (also known as Age-Related Cognitive Decline), and other age-related impairments of, and/or changes in, cognitive function. The method comprises administering to a subject a therapeutically effective amount of a lipid-soluble thiamine or a prodrug thereof in an amount averaging from about 0.02 to about 0.5 grams per day per 70 kg body weight over a period of three months or longer.
Claims7
A method of treating conditions of the central nervous system, said method comprising administering to a subject a therapeutically effective amount of a lipid-soluble thiamine or a prodrug thereof selected from the group consisting of thiamine tetrahydrofuryl disulfide, thiamine allyl disulfide, thiamine (7-methoxycarbonyl-3-acetylthioheptyl) disulfide, thiamine 2-hydroxyethyl disulfide and O-benzoylthiamine disulfide, said lipid-soluble thiamine being administered in an amount averaging from about 0.02 to about 0.5 grams per day per 70 kg body weight over a period of at least three months.
Dependencies are inferred from the claim text.