Hepatitis GB Virus synthetic peptides and uses thereof
AssigneeAbbott Laboratories
InventorsGeorge J. Dawson, Tami J. Pilot-Matias, Dominique P. Bridon, Pamella A. Schroeder-Poliak, Mark F. Knigge, Keeve D. Jaffe, Isa K. Mushahwar
Life of this patent
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Abstract
Hepatitis GB Virus (HGBV) synthetic peptides useful for a variety of diagnostic and therapeutic applications, kits for using the HGBV nucleic acid or amino acid sequences and antibodies which specifically bind to HGBV. Also provided are methods for producing antibodies, polyclonal or monoclonal, from the HGBV peptides.
Claims15
A purified polypeptide of hepatitis GB virus (HGBV) prepared by synthetic means wherein said polypeptide is SEQUENCE I.D. NO. 5.
A purified polypeptide of hepatitis GB virus (HGBV) prepared by synthetic means wherein said polypeptide is s fragment having at least 8 contiguous amino acids of SEQUENCE I.D. NO. 5.
An assay kit useful for determining the presence of hepatitis GB virus (HGBV) antigen or antibody in a test sample, comprising a container containing a polypeptide prepared by synthetic means, wherein said polypeptide is SEQUENCE I.D. NO. 5.
An assay kit useful for determining the presence of hepatitis GB virus (HGBV) antigen or antibody in a test sample, comprising a container containing a polypeptide prepared by synthetic means, wherein said polypeptide is a fragment having at least 8 contiguous amino acids of SEQUENCE I.D. NO. 5.
A method for producing antibodies to hepatitis GB virus (HGBV) comprising administering to an individual an isolated immunogenic polypeptide produced by synthetic means, wherein said polypeptide is SEQUENCE I.D. NO. 5.
A method for producing antibodies to hepatitis GB virus (HGBV) comprising administering to an individual an isolated immunogenic polypeptide produced by synthetic means, wherein said polypeptide is a fragment having at least 8 contiguous amino acids of SEQUENCE I.D. NO. 5.
A diagnostic reagent comprising a polypeptide of hepatitis GB virus (HGBV), wherein said polypeptide is (a) produced by synthetic means, (b) SEQUENCE I.D. NO. 5, and (c) attached to a solid support.
A diagnostic reagent comprising a polypeptide of hepatitis GB virus (HGBV), wherein said polypeptide is (a) produced by synthetic means, (b) a fragment having at least 8 contiguous amino acids of SEQUENCE I.D. NO. 5, and (c) attached to a solid support.
Dependencies are inferred from the claim text.