Use of endothelial-leukocyte adhesion molecule-1 specific antibodies in the treatment of asthma
AssigneeBoehringer Ingelheim GmbH
InventorsRobert H. Gundel, Craig D. Wegner, L. Gordon Letts, C. Wayne Smith
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Abstract
A method for treating asthma in a patient using an agent selected from the group consisting of: (a) an antibody capable of binding to ELAM-1; (b) a fragment of the antibody (a), the fragment being capable of binding to ELAM-1; (c) ELAM-1, being substantially free of natural contaminants; (d) a functional derivative of ELAM-1; (e) an antibody capable of binding to an ELAM-1 receptor; (f) a fragment of the antibody (e), the fragment being capable of binding to an ELAM-1 receptor; (g) an ELAM-1 receptor, being substantially free of natural contaminants; and . (h) a functional derivative of an ELAM-1 receptor.
Claims2
A method for treating asthma in a patient which comprises administering to the patient an effective therapeutic amount of an antigen-binding antibody which specifically binds to ELAM-1 or an antigen-binding fragment thereof.
Dependencies are inferred from the claim text.