Glycopeptide antibiotic derivatives
AssigneeEli Lilly and Company
InventorsRobin D. G. Cooper, Bret E. Huff, Thalia I. Nicas, John T. Quatroche, Michael J. Rodriguez, Nancy J. Snyder, Michael A. Staszak, Richard C. Thompson, Stephen C. Wilkie, Mark J. Zweifel
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Abstract
The present invention provides glycopeptide antibiotic derivative compounds. These derivative compounds possess antibacterial activity against a wide variety of bacteria, including activity against vancomycin-resistant isolates. Methods of making and using these glycopeptide antibiotic derivative compounds are also provided.
Claims7
A compound of the formula:
- ##STR9## or a salt thereof.
A pharmaceutical composition comprising 4 4 chlorophenyl!benzyl-A82846B, wherein the 4-4-chlorophenyl!benzyl is on the amino group of the 4 epi-vancosaminyl sugar of the 4-epi-vancosaminyl-O-glycosyl disaccharide or a salt thereof.
Dependencies are inferred from the claim text.