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US 5,837,859 AGranted
Preparation of a electronically conductive polymer/nucleotide copolymer
AssigneeCIS Bio International
InventorsRobert Teoule, Andre Roget, Thierry Livache, Christelle Barthet, Gerard Bidan
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Abstract
A copolymer of general formula (I), ##STR1## wherein unit A is a monomer of an electronically conductive polymer, unit B is a nucleotide, an oligonucleotide or an analogue thereof, x, y, z are integers of 1 or higher or y is 0, and l is a covalent bond, or a spacer arm. Methods for preparing said polymer and its use, in particular for nucleic acid synthesis, sequencing and hybridization, are also disclosed.
Claims9
A process for preparing an electrically conductive copolymer represented by general formula (1):
- ##STR5## comprising copolymerizing a monomer represented by formula (IV):
- ##STR6## with a polymerizable monomer represented by the formula A, wherein said monomer A produces an electrically conductive polymer when polymerized, and represents a polymerized unit of said monomer A in the electrically conductive copolymer,
- represents either (1) a nucleotide unit or an analog thereof, or (2) an oligonucleotide unit or an analog thereof,
- x, y and z each, independently, represents an integer equal to or greater than 1, and l represents a covalent bond or a spacer arm.
1 more element
Dependencies are inferred from the claim text.