A method for the free radical polymerization of biocompatible starting materials characterized by having a reactive functionality thereon, wherein said biocompatible starting materials are selected from polysaccharides, polycations, or lipids, said method comprising:
- chemically modifying said biocompatible starting material in aqueous media consisting essentially of water and solutes with a reactive species capable of free radical polymerization, thereby creating a modified biocompatible material capable of forming covalent crosslinks;
- and
- contacting said modified biocompatible material with a free radical initiating system under biocompatible, free radical producing conditions in aqueous media consisting essentially of water and solutes, or consisting essentially of water, solutes, and a biocompatible oil.