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US 5,837,379 AGranted
Once daily pharmaceutical tablet having a unitary core
AssigneeAndrx Pharmaceuticals, Inc.
InventorsChih-Ming Chen, Joseph C. H. Chou
Life of this patent
Estimating the term…
Abstract
A controlled release nifedipine tablet which comprises: (a) a homogeneous compressed core which comprises: (i) a medicament; (ii) a water soluble osmotic compound (iii) one or more osmotic polymers; and (b) a membrane coating which completely covers said core tablet which comprises a mixture of: (i) a water insoluble pharmaceutically acceptable polymer; and (ii) an enteric polymer.
Claims15
A once a day controlled release tablet which comprises:
- (a) a homogeneous compressed core of granules produced in a fluidized bed, said core said core comprising:
- (i) a medicament;
- (ii) a water soluble osmotic compound;
- (iii) one or more osmotic polymers wherein one of the osmotic polymers is a water swellable osmotic polymer;
- and
- (b) a membrane coating which completely covers said core tablet which comprises a mixture of:
- (i) a water insoluble pharmaceutically acceptable polymer;
- and
- (ii) an enteric polymer.
6 more elements
A once a day controlled release nifedipine tablet which comprises:
- (a) a homogeneous compressed core made from granules produced in a fluidized bed process said core consisting essentially of:
- (i) nifedipine;
- (ii) a water soluble osmotic compound;
- (iii) polyethylene oxide;
- and
- (b) a membrane coating which completely covers said core tablet which comprises a mixture of:
- (i) a water insoluble pharmaceutically acceptable polymer;
- and
- (ii) an enteric polymer.
6 more elements
A once a day controlled release tablet which comprises:
- (a) a homogeneous compressed core of granules produced in a fluidized bed, said core said core consisting essentially of:
- (i) a medicament;
- (ii) a water soluble osmotic compound;
- (iii) one or more osmotic polymers wherein one of the osmotic polymers is a water swellable osmotic polymer;
- and
- (b) a membrane coating which completely covers said core tablet which comprises a mixture of:
- (i) a water insoluble pharmaceutically acceptable polymer;
- and
- (ii) an enteric polymer.
6 more elements
Dependencies are inferred from the claim text.