Polymeric drug delivery system
AssigneeMonsanto Company
InventorsSamuel J. Tremont, Paul Waddell Collins, William Eldredge Perkins, Peter Hadley Jones
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Abstract
A drug delivery system adapted to release an effective amount of a drug at pH values of about 1 to 7 without releasing a significant amount of the drug at pH values of about 7 and above, the system comprising a polymeric material and a drug covalently bonded to the polymeric material through a pH sensitive covalent bond capable of being cleaved in the pH range of 1 to about 7.
Claims31
A delivery system for releasing an active ingredient at pH values up to about 7 and for inhibiting release of the active ingredient at pH values above 7, the system, comprising a polymeric material covalently bonded to the active ingredient through a covalent bond that is pH sensitive and capable of being cleaved at pH values up to about 7.
Dependencies are inferred from the claim text.