2'-4'-h alo-1,1'-biphenyl!-4-yl!methyl!-5'-methyl-spirocyclopentane-1,7' (8'H)-3H! imidazo2,1-b!purin!-4' (5'H)-ones
AssigneeSchering Corporation
InventorsBrian A. McKittrick, Deen Tulshian
Life of this patent
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Abstract
Antihypertensive and bronchodilating phosphoclusterose inhibitory compounds of the formula ##STR1## or a pharmaceutically acceptable salt thereof wherein X is fluoro, chloro or bromo.
Claims6
A compound having the structural formula ##STR28## or a pharmaceutically acceptable salt thereof, wherein:
- X is chloro, fluoro or bromo.
2'-4'-Fluoro-1,1'-biphenyl!-4-yl!methyl!-5'-methyl-spiroc yclopentane-1,7'(8'H)-3H!imidazo-2,1-b!purin!-4'(5'H)-one.
2'-4'-Chloro-1,1'-biphenyl!-4-yl!methyl!-5'-methyl-spi rocyclopentane-1,7'(8'H)-3H!imidazo-2,1-b!purin!-4'(5'H)-one.
2'-4'-Bromo-1,1'-biphenyl!-4-yl!methyl!-5'-methyl-spirocy clopentane-1,7'(8'H)-3H!imidazo-2,1-b!purin!-4'(5'H)-one.
Dependencies are inferred from the claim text.