Topical composition containing a substance P antagoinst
AssigneeL'oreal
InventorsOlivier De Lacharriere, Lionel Breton
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Abstract
The invention relates to a therapeutic composition for topical application containing at least one product with an irritant side effect and a substance P antagonist for reducing or even eliminating the irritant effect of this product. It also relates to the use of a substance P antagonist for the preparation of a pharmaceutical composition for topical application containing at least one product with an irritant side effect for reducing or even eliminating the irritant effect of this product. The substance P antagonist may be a peptide compound or a nitrogen-containing compound or a nitrogen-, sulphur- or oxygen-containing heterocyclic compound.
Claims16
A method of treating or preventing irritation to sensitive skin which occurs upon topical administration of at least one product which normally elicits an irritant side effect to sensitive skin if topically administered in the absence of an effective amount of a substance P antagonist, which comprises topically administering to a subject having sensitive skin a composition comprising (i) said product which normally elicits an irritant side effect, upon topical application to sensitive skin (ii) an amount of at least one substance P antagonist sufficient to reduce or eliminate said irritant side effect, and (iii) a pharmaceutically acceptable medium.
Dependencies are inferred from the claim text.