Antiproliferative protein from Bacillus thuringiensis var. thuringiensis
AssigneesResearch Development Corporation, Universidad Autonoma de Nuevo Leon
InventorsBharat B. Aggarwal, Cristina Rodriguez-Padilla
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Abstract
The present invention provides an isolated and purified protein derived from Bacillus thuringiensis subspecies thuringiensis, having a molecular weight of approximately 20 kDa of SDS-PAGE, said protein having the partial amino acid sequence shown in SEQ ID No. 1, and wherein said protein displays cytotoxic effects against tumor cells. Also provided is a method of treating a neoplastic cell comprising administering a therapeutically effective dose of the composition of the present invention to said cell.
Claims11
An isolated and purified protein derived from Bacillus thuringiensis subspecies thuringiensis, having a molecular weight of approximately 20 kDa as determined by SDS-PAGE, said protein having the partial amino acid sequence shown in SEQ ID No. 1, and wherein said protein displays cytotoxic effects against tumor cells.
Dependencies are inferred from the claim text.