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AssigneeCiencia, Inc.
InventorsSalvador M. Fernandez, Ernest St. Louis, Ralph Levy, Ernest F. Gulgon, Sean Cobane
Estimating the term…
A phase fluorometer employs a baseband frequency generator to generate a sample baseband signal at a first frequency f.sub.o and a reference signal correlated to the sample baseband signal. A second signal generator generates a carrier signal having a second frequency f. The sample baseband signal and the carrier signal are combined to form an up-converted sample signal having a frequency f.+-.f.sub.o. A light source is modulated at the up-converted sample signal frequency f.+-.f.sub.o to illuminate a sample. A photo detector detects fluorescence emissions from a sample excited by the excitation light and converts the emission into a fluorescence signal. A down-converter combines the carrier signal and fluorescence signal to form a phase-shifted and down-converted sample signal. A processor digitally processes the phase-shifted and demodulated sample signal and the reference signal to determine the fluorescence lifetime.
A method of measuring the phase of a sample signal relative to a reference signal comprising:
A phase fluorometer comprising:
An instrument for detecting a phase shift comprising:
A method of measuring the phase of a sample signal relative to a reference signal comprising:
A phase fluorometer comprising:
Dependencies are inferred from the claim text.