Particle settler for use in cell culture
AssigneeBioscot Limited
InventorsKeith John Thompson, James Samuel Wilson
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Abstract
Disclosed is a device for separating particles from a bulk liquid, such as viable hybridoma cells from antibody-containing liquid medium. The device comprises a plurality of settlement plates, or other surfaces, being inclined to the vertical, and a pump or other means for causing liquid containing the particles to flow upwardly over the surfaces at such a rate as to allow particles to be separated from the bulk liquid to form sediment layers on the surfaces and slide down them for collection at an appropriate point.
Claims31
A device for separating particles from a bulk liquid under aseptic or sterile conditions, the device comprising means defining a plurality of settlement surfaces, the surfaces being inclined to the vertical, and means for causing liquid containing the particles to flow upwardly over said surfaces at such a rate as to allow particles to be separated from the bulk liquid to form sediment layers on the surfaces and slide down them, wherein said surfaces and said means for causing the liquid to flow upwards are contained within a sterile housing.
Dependencies are inferred from the claim text.