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AssigneeCare Wise Medical Products Corporation
InventorRobert G. Carroll
Estimating the term…
A system and method for providing external therapy radiation to radioactively tagged cancerous tissue via a radiation therapy machine. The system includes at least one radiation detector, e.g., a probe or gamma camera, and an analyzer, which is(are) arranged to be mounted with respect to the radiation therapy machine so that it(they) is(are) located adjacent the patient for receiving gamma rays and characteristic x rays emitted from the tagged cancerous tissue and for providing a signal representative thereof to the analyzer. The signal includes a first portion representing the characteristic x rays received from the tagged tissue and a second portion representing the gamma rays received therefrom. The portion of the signal corresponding to Compton-scattered photons is removed in the region of the full-energy gamma ray and in the region of the characteristic x ray. The analyzer uses selected portions of the signal to provide near-field information about the cancerous tissue, far-field information about the cancerous tissue, and extended field information about the cancerous tissue. This information is provided to the radiation therapy machine to control its operation so that it can irradiate the localized cancerous tissue from various directions to destroy the localized cancerous tissue, with minimal damage to adjacent viable normal tissue.
A system for providing precise therapy radiation to living tumor tissue within the body of a living being, said system comprising a tumor localizing radiopharmaceutical, a controllable source of therapy radiation, and radiation detecting means, said tumor localizing radiopharmaceutical being attached to the living tumor tissue, whereupon said radiopharmaceutical produces tumor-localizing radiation from the living tumor tissue, said tumor-localizing radiation comprising photons of different energies, including gamma radiation, x radiation, and/or annihilation radiation, produced by said radiopharmaceutical, said controllable source of therapy radiation being arranged for providing at least one gamma or x ray or particulate therapy beam, said radiation detecting means being arranged to be brought into various positions adjacent the body of the being for detecting said tumor localizing radiation from a plurality of directions and utilizing the known naturally occurring abundance of emitted photons of different energies of said radiopharmaceutical as a reference factor to provide an indication of the three dimensional distribution of the living tumor tissue to which said radiopharmaceutical is attached and for providing a signal indicative thereof, said controllable source of therapy radiation being arranged for receipt of said signal to precisely direct said at least one beam of said therapy radiation to the living tumor tissue to which said radiopharmaceutical is attached, whereupon said at least one beam of said therapy radiation necrotizes that tissue with minimal damage to adjacent viable tissue.
A system for providing precise therapy radiation to living tumor tissue within the body of a living being provided with a tumor localizing radiopharmaceutical attached to the living tumor tissue, the radiopharmaceutical emitting tumor-localizing radiation of different energies comprising photons of different energy, including gamma radiation, x radiation, and/or annihilation radiation, from the living tumor tissue to which said radiopharmaceutical has attached, said system comprising a controllable source of therapy radiation, and radiation detection means, said radiation detecting means being arranged to be brought into various positions adjacent the body of the being for detecting the emitted radiation from said radiopharmaceutical from a plurality of directions and utilizing the known naturally occurring abundance of emitted radiation of different energies of said radiopharmaceutical as a reference factor to provide an indication of the three dimensional distribution of the living tumor tissue to which said radiopharmaceutical is attached and for providing an electrical signal indicating the three dimensional distribution of the living tumor tissue to which the radiopharmaceutical is attached, irrespective of the location thereof within the body of the living being, said controllable source of therapy radiation being arranged for providing at least one gamma or x ray or particulate therapy beam and being arranged for receipt of said electrical signal to precisely direct said at least one therapy beam to the living tumor tissue to which said radiopharmaceutical is attached, whereupon said at least one therapy beam necrotizes that tissue with minimal damage to adjacent viable tissue.
A system for providing precise therapy radiation to living tumor tissue within the body of a living being provided with a tumor localizing radiopharmaceutical attached to the living tumor tissue, the radiopharmaceutical emitting gamma-ray photons, characteristic x-ray photons, and an associated continuum of Compton-scattered photons from the living tumor tissue to which said radiopharmaceutical is attached, said system comprising a controllable source of therapy radiation, and radiation detection means, said radiation detecting means being arranged to be brought into various positions adjacent the body of the being for detecting the characteristic x rays and the gamma rays from a plurality of directions to provide an indication of the three dimensional distribution of the living tumor tissue to which said radiopharmaceutical is attached and for providing an electrical signal indicating the three dimensional distribution of the living tumor tissue to which the radiopharmaceutical is attached, irrespective of the location thereof within the body of the living being, said controllable source of therapy radiation being arranged for providing at least one gamma or x ray or particulate therapy beam and being arranged for receipt of said electrical signal to precisely direct said at least one therapy beam to the living tumor tissue to which said radiopharmaceutical is attached to necrotize that tissue with minimal damage to adjacent viable tissue.
A system for providing precise therapy radiation to living tumor tissue within the body of a living being comprising a tumor localizing radiopharmaceutical, a controllable source of beam radiation, and radiation detection means, said tumor localizing radiopharmaceutical being radioactive prior to introduction into the body of the being and arranged for provision into the body of the living being for attachment to the living tumor tissue within the body of the being, whereupon said radiopharmaceutical provides tumor-localizing radiation from the living tumor tissue to which said radiopharmaceutical has attached, said tumor-localizing radiation comprising photons of different energies produced by said radiopharmaceutical, including gamma radiation, x radiation, and/or annihilation radiation, said radiation detecting means being arranged to be brought into various positions adjacent the body of the being for detecting said tumor localizing radiation from a plurality of directions and utilizing the known naturally occurring abundance of emitted photons of different energies of said radiopharmaceutical as a reference factor to provide an indication of the three dimensional distribution of the living tumor tissue to which said radiopharmaceutical has attached and for providing a signal indicative thereof, said controllable source of therapy radiation being arranged for receipt of said signal to precisely direct at least one beam of said therapy radiation to the living tumor tissue to which said radiopharmaceutical has attached, whereupon said at least one beam necrotizes that tissue with minimal damage to adjacent viable tissue.
A method of providing precise therapy radiation to living tumor tissue within the body of a living being from an external, controllable source of therapy beam radiation, said method comprising a tumor localizing radiopharmaceutical attached to the living tumor tissue within the body of the being, whereupon said radiopharmaceutical provides tumor-localizing radiation from that tissue, said tumor-localizing radiation comprising photons of different energies produced by said radiopharmaceutical, including gamma radiation, x radiation, and/or annihilation radiation, detecting said tumor-localizing radiation from a plurality of directions, utilizing the known naturally occurring abundance of emitted photons of different energies of said radiopharmaceutical as a reference factor to provide an indication of the three dimensional distribution of the living tumor tissue to which said radiopharmaceutical is attached, and utilizing said indication of the three dimensional distribution of the living tumor tissue to precisely direct at least one beam of said therapy radiation thereto, whereupon said at least one beam of therapy radiation necrotizes that tissue with minimal damage to adjacent viable tissue.
Dependencies are inferred from the claim text.