Lipid based composition containing diacylglycerol, phospholipid, polar liquid and biologically active material

A biologically active composition which is glycerol-ester-based containing

• (a) at least one diacyl glycerol, wherein the acyl groups, which are the same or different, are each derived from an unsaturated fatty acid having 16-22 carbon atoms, or from a saturated fatty acid having 8-10 carbon atoms,
• (b) at least one phospholipid selected from glycerophosphatides and sphingophosphatides, wherein the acyl groups, which are the same or different, are each derived from a fatty acid having 14-22 carbon atoms, and optionally,
• (c) at least one polar liquid selected from the group consisting of water, glycerol, ethylene glycol and propylene glycol, the proportions between the components (a), (b) and optionally (c) being such that they together form an L2-phase or a cubic liquid crystalline phase, wherein (c) is an optional component in the case of L2-phase and a requisite component in the case of cubic liquid crystalline phase, and
• (d) a biologically active material being dissolved or dispersed in said L2-phase or said cubic liquid crystalline phase.