Polymer matrix drug delivery apparatus
AssigneeCorTrak Medical, Inc.
InventorsJ. Edward Shapland, Keith R. Hildelbrand, Joel R. Racchini, Jin Shimada, Mark B. Knudson
Life of this patent
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Abstract
A drug delivery apparatus and method for delivering a drug locally to internal body tissue using a catheter device including a polymer matrix containing a drug. The drug is actively transported from the polymer matrix to the internal body tissue using iontophoresis or phonophoresis. In addition, the polymer matrix can be expanded to promote intimate contact with the walls of a passageway or vessel.
Claims10
An apparatus for delivering a drug to internal body tissue of a patient, the apparatus comprising:
- a catheter having an elongated body;
- a polymer matrix operably connected to and coaxially aligned with the elongated body, the polymer matrix being substantially non-compressible and configured to embody the drug, the polymer matrix selected from the group consisting essentially of polyethylene oxide, polyacrylamide, polyurethane rubber, and natural rubber;
- and
- transport means operably connected to the catheter, the transport means being configured to actively transport the drug from the polymer matrix to the internal body tissue.
An apparatus for delivering a drug to internal body tissue of a patient, the apparatus comprising:
- a catheter having an elongated body;
- a polymer matrix operably connected to the elongated body, the polymer matrix being substantially non-compressible and configured to embody the drug, the polymer matrix selected from the group consisting essentially of polyethylene polyetheline oxide, polyacrylamide, polyurethane rubber, and natural rubber;
- expansion means operably connected to the elongated body, the expansion means being configured to expand the polymer matrix in a direction substantially radial to the catheter;
- and
- transport means operably connected to the catheter, the transport means being configured to actively transport the drug from the polymer matrix to the internal body tissue.
An apparatus for delivering a drug to internal body tissue of a patient, the apparatus comprising:
- a catheter having a balloon;
- a polymer matrix operably connected to the balloon, the polymer matrix being substantially non-compressible and configured to embody the drug, the polymer matrix selected from the group consisting essentially of polyethylene oxide, polyacrylamide, polyurethane rubber, and natural rubber;
- and
- first and second electrodes configured to be placed in electrical communication to a power supply, the first electrode being positioned for electrical communication with the polymer matrix.
Dependencies are inferred from the claim text.