Multi-well culture dish assembly

A culture dish assembly comprising:

• a well plate defining a plurality of wells;
• an insert including a top wall, a peripheral flange extending downwardly from said top wall, said peripheral flange including an upper portion and a lower portion, and a plurality of enclosures coupled to said top wall, each of said enclosures including an upper end defining an upper opening, a lower end defining a bottom opening, a side wall connecting said upper and lower ends, a semi-permeable membrane mounted to said lower end and covering said bottom opening, a plurality of wall openings in said top wall, each of said wall openings adjoining one of said enclosures, each of said enclosures including a radial opening extending through said side wall and said upper end, each of said side walls including a substantially vertical portion adjoining said radial opening and extending towards said lower end, said radial openings each adjoining one of said wall openings and defining therewith a plurality of pipette openings, said insert being mountable to said well plate such that said enclosures are respectively positioned within and radially offset with respect to said wells, and a lid including a top wall and a downwardly depending peripheral flange, said lid being mountable to said insert such that said top wall of said lid engages said upper ends of said enclosures, said peripheral flange of said lid overlies said upper portion of said peripheral flange of said insert and said lower portion of said peripheral flange of said insert is accessible beneath said peripheral flange of said lid, thereby allowing said insert and lid to be removed from or applied to said well plate as a unit.