Preparation for improving the blood supply containing hard magnetic particles

A process for the manufacture of a preparation for stimulating the blood circulation of the skin comprising

• incorporating magnetically hard single-domain particles with a strong coercive field and with a size in the range of 600 to 1200 nm into a pharmaceutically or cosmetically acceptable excipient or additive to form a dispersion;
• and
• wherein the magnetically hard single-domain particles are selected from the group consisting of barium hexaferrite, strontium hexaferrite, undoped barium hexaferrite, undoped strontium hexaferrite, and the mixtures thereof;
• incorporating the magnetically hard single-domain particles into the excipient in combination with asymmetric lamellar aggregates consisting of phospholipids with a phosphatidylcholine content in the range of 30% to 99% by weight and oxygen-charged fluorocarbons in the range of 0.2% to 100% (weight/volume);
• with the optional addition of dispersants used to form said dispersion;
• wherein said dispersion contains a proportion of magnetically hard single-domain particles in the range 0.01% to 70% by weight, based on the total weight of the dispersion;
• and
• wherein the balance up to 100% by weight is said excipient or additive, based upon the total weight of said dispersion.