Close vascularization implant material
AssigneeBaxter International Inc.
InventorsJames H. Brauker, Robert C. Johnson, Laura A. Martinson, Ronald S. Hill
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Abstract
A device for implantation in a host having a material at an interface between the host and the device, said material having a conformation which results in growth of vascular structures by the host close to the interface.
Claims11
A device for implantation in a host having a material at an interface between the host and the device, said material having (a) a nominal pore size from about 0.6 to about 20 microns which comprise frames of elongated strands of material that are less than 5 microns in all but the longest dimension wherein said frames define apertures which interconnect to form three-dimensional cavities which permit substantially all host inflammatory cells migrating into the cavities to maintain a rounded morphology;
- and (b) a conformation which results in growth of vascular structures by the host close to but not substantially into the interface.
A device for implantation in a host having a first material at an interface between the host and the device, said first material having (a) a nominal pore size ranging from about 0.6 to about 20 microns which comprise frames of elongated strands of material that are less than 5 microns in all but the longest dimension wherein said frames define apertures which interconnect to form three-dimensional cavities which permit substantially all host inflammatory cells migrating into the cavities to maintain a rounded morphology;
- and (b) a conformation which results in growth of vascular structures by the host close to but not substantially into the interface, the device further having a second material underlying the first material, the second material being impermeable to immune factors.
Dependencies are inferred from the claim text.