Method of measuring the effect of a dialysis treatment
AssigneeGambro AB
InventorJan Sternby
Life of this patent
Estimating the term…
Abstract
Methods for measuring the effect of dialysis treatments are disclosed in which a fraction of the used dialysis fluid is extracted downstream of the dialyzer for analysis of at least one substance such as urea, and in which the fraction of dialysis fluid is extracted through a branch conduit containing a pump. In accordance with this method, the total amount of used dialysis fluid is measured and the concentration of that substance in the extracted fraction is measured, and the total amount of that substance removed from the patient can then be calculated from these values. This invention is preferably intended for use in connection with hemodialysis, hemofiltration and hemodiafiltration.
Claims56
A method of measuring the effect of a hemodialysis, hemodiafiltration or hemofiltration treatment, comprising:
- extracting a measurable substance from blood with a flow of a dialysis fluid in a dialyzer so as to produce a continuous flow of dialysate fluid including said measurable substance, continuously measuring the actual flow rate of said dialysate fluid whereby the total amount of said dialysate fluid is determined therefrom, continuously withdrawing a fraction of said dialysate fluid at a rate which always bears the same proportional relationship to said measured flow rate of said dialysate fluid such that the concentration of said measurable substance in said fraction is substantially the same as the concentration of said measurable substance in said dialysate fluid, said fraction being withdrawn downstream of said dialyzer, measuring the concentration of said measurable substance in said fraction, and calculating the total amount of said measurable substance removed by said dialysate fluid based on said total amount of said dialysate fluid and said concentration of said measurable substance in said fraction.
A method of measuring the effect of a hemodialysis, hemodiafiltration or hemofiltration treatment, comprising:
- extracting a measurable substance from blood with a flow of a dialysis fluid in a dialyzer so as to produce a continuous flow of dialysate fluid including said measurable substance, continuously measuring the actual flow rate of said dialysate fluid whereby the total amount of said dialysate fluid is determined therefrom, intermittently withdrawing a fraction of said dialysate fluid at a rate which always bears the same proportional relationship to said measured flow rate of said dialysate fluid such that the concentration of said measurable substance in said fraction is substantially the same as the concentration of said measurable substance in said dialysate fluid, said fraction being withdrawn downstream of said dialyzer, measuring the concentration of said measurable substance in said fraction, and calculating the total amount of said measurable substance removed by said dialysate fluid based on said total amount of said dialysate fluid and said concentration of said measurable substance in said fraction.
A method of measuring the effect of a hemodialysis, hemodiafiltration or hemofiltration treatment, comprising:
- extracting a measurable substance from blood with a flow of a dialysis fluid in a dialyzer so as to produce a continuous flow of dialysate fluid including said measurable substance, continuously measuring the actual flow rate of said dialysate fluid whereby the total amount of said dialysate fluid is determined therefrom, continuously withdrawing a fraction of said dialysate fluid at a rate which always bears the same proportional relationship to said measured flow rate of said dialysate fluid such that the concentration of said measurable substance in said fraction is substantially the same as the concentration of said measurable substance in said dialysate fluid, said fraction being withdrawn downstream of said dialyzer, measuring the total volume of said fraction of said dialysate fluid and the total amount of said measurable substance in said fraction of said dialysate fluid, whereby the concentration of said measurable substance in said dialysate fluid can be calculated and calculating the total amount of said measurable substance removed by said dialysate fluid based on said total amount of said dialysate fluid and said concentration of said measurable substance in said fraction.
A method of measuring the effect of a hemodialysis, hemodiafiltration or hemofiltration treatment, comprising:
- extracting a measurable substance from blood with a flow of a dialysis fluid in a dialyzer so as to produce a continuous flow of dialysate fluid including said measurable substance, continuously measuring the actual flow rate of said dialysate fluid whereby the total amount of said dialysate fluid is determined therefrom, intermittently withdrawing a fraction of said dialysate fluid at a rate which always bears the same proportional relationship to said measured flow rate of said dialysate fluid such that the concentration of said measurable substance in said fraction is substantially the same as the concentration of said measurable substance in said dialysate fluid, said fraction being withdrawn downstream of said dialyzer, measuring the total volume of said fraction of said dialysate fluid and the total amount of said measurable substance in said fraction of said dialysate fluid, whereby the concentration of said measurable substance in said dialysate fluid can be calculated and calculating the total amount of said measurable substance removed by said dialysate fluid based on said total amount of said dialysate fluid and said concentration of said measurable substance in said fraction.
Dependencies are inferred from the claim text.