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US 5,786,148 AGranted
Polynucleotides encoding a novel prostate-specific kallikrein
AssigneeIncyte Pharmaceuticals, Inc.
InventorsOlga Bandman, Surya K. Goli
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AssigneeIncyte Pharmaceuticals, Inc.
InventorsOlga Bandman, Surya K. Goli
Estimating the term…
The present invention provides a human prostate-specific kallikrein (HPSK) and polynucleotides which identify and encode HPSK. The invention also provides genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding HPSK and a method for producing HPSK. The invention also provides for agonists, antibodies, or antagonists specifically binding HPSK, and their use, in the prevention and treatment of diseases associated with expression of HPSK. Additionally, the invention provides for the use of antisense molecules to polynucleotides encoding HPSK for the treatment of diseases associated with the expression of HPSK. The invention also provides diagnostic assays which utilize the polynucleotide, or fragments or the complement thereof, and antibodies specifically binding HPSK.
An isolated and purified polynucleotide sequence encoding a prostate-specific kallikrein comprising the amino acid sequence of SEQ ID NO:1.
An isolated and purified polynucleotide sequence comprising SEQ ID NO:2.
A polynucleotide sequence which is complementary to SEQ ID NO:2.
Dependencies are inferred from the claim text.