DNA fragment coding for squamous cell carcinoma-associated antigen
AssigneeDainabot Co., Ltd.
InventorsYoshinori Suminami, Hiroshi Kato, Kiyoshi Sekiguchi, Katsumichi Takeda
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Abstract
A DNA fragment coding for squamous cell carcinoma-associated antigen is first isolated and prepared by DNA recombination techniques. The fragments thus obtained are useful as diagnostic reagents for the squamous cell carcinoma and as immunogens.
Claims6
A method for recombinant production of human squamous cell carcinoma-associated antigen which comprises cultivating a host cell containing an expression vector comprising an isolated nucleic acid consisting of a nucleotide sequence coding for a polypeptide having an amino acid sequence of any one of SEQ ID NO:12, SEQ ID NO:13, SEQ ID NO:14, SEQ ID NO:15, SEQ ID NO:16 or SEQ ID NO:17, under conditions for sufficient for expression of said polypeptide.
An isolated nucleic acid consisting of SEQ ID NO:3.
An isolated nucleic acid consisting of SEQ ID NO:4.
An isolated nucleic acid consisting of SEQ ID NO:5.
An isolated nucleic acid consisting of SEQ ID NO:6.
An isolated nucleic acid consisting of a nucleotide sequence encoding an antigen consisting of the amino acid sequence of SEQ ID NO:2.
Dependencies are inferred from the claim text.