Pharmaceutical bottle of two separate substances with mixing device, dosed application and assembly process thereof

A container, comprising:

• a) a top container open at a top end and closed at a bottom end opposite the top end by a tearable seal;
• b) a bottom container having a perimetric shoulder, the shoulder sized and shaped to center automatically the top container and the bottom container during assembly, the bottom container closed at a bottom end and open at a top end opposite the bottom end, the top end defined by a tubular neck having a peripheral edge containing a first set of stria;
• c) a flap extending radially out from an exterior of the top container so that the flap surrounds the neck of the bottom container when the top container is inserted into the interior of the tubular neck, an interior of the flap having a second set of stria that engage the first set of stria;
• and
• d) a tubular sleeve having a bottom end and a top end, the bottom end defined by a beveled edge and the top end closed by a truncated cone, the bottom end of the tubular sleeve being sized and shaped to be received within the open end of the top container;
• wherein the tubular sleeve may be moved axially within the top container so that the beveled edge tears the tearable seal in the top container.

A container, comprising:

• a) a bottom container closed at a bottom end and open at a top end opposite the bottom end, the top end defined by a tubular neck having a peripheral edge containing a first set of stria;
• b) a top container open at a top end and closed at a bottom end opposite the top end by a tearable seal;
• c) a flap extending radially out from an exterior of the top container so that the flap surrounds the neck of the bottom container when the top container is inserted into the interior of the tubular neck, an interior of the flap having a second set of stria that engage the first set of stria;
• and
• d) a tubular sleeve having a bottom end and a top end, the bottom end defined by a beveled edge and the top end closed by a means for threadably coupling the container to a medical tool, the bottom end of the tubular sleeve being sized and shaped to be received within the open end of the top container;
• wherein the tubular sleeve may be moved axially within the top container so that the beveled edge tears the tearable seal in the top container.