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US 5,777,060 AGranted
Silicon-containing biocompatible membranes
AssigneeMiniMed Inc.
InventorWilliam Peter Van Antwerp
Life of this patent
Estimating the term…
Abstract
Biocompatible membranes for use with biosensors are provided. The membranes are polymers which can be prepared from (a) a diisocyanate, (b) a hydrophilic polymer, (c) a siloxane polymer having functional groups at the chain termini, and optionally, (d) a chain extender.
Claims9
A biocompatible membrane formed from a reaction mixture of:
- (a) a diisocyanate, said diisocyanate comprising about 50 mol % of the reactants in said mixture;
- (b) a hydrophilic polymer which is a member selected from the group consisting of a hydrophilic polymer diol, a hydrophilic polymer diamine and combinations thereof;
- (c) a siloxane polymer having functional groups at the chain termini, said membrane having a glucose diffusion coefficient of from about 1.times.10.sup.-9 cm.sup.2 /sec to about 200.times.10.sub.-9 cm.sup.2 /sec, a water pickup of at least 25% and a ratio of D.sub.oxygen /D.sub.glucose of from about 5 to about 200.
Dependencies are inferred from the claim text.