Immunosuppressant compounds
AssigneeThe University of Nottingham
InventorsBarrie Walsham Bycroft, Herbert Fitzgerald Sewell, Gordon Sydney Anderson Birnie Stewart, Paul Williams
Life of this patent
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Abstract
A compound having formula (1) for use as a medicament wherein n is 2 or 3; Y is O, S or NH; X is O, S or NH; and R is C.sub.1 -C.sub.18 alkyl or acyl which may be substituted. ##STR1##
Claims14
A method for treating an allergic or autoimmune disease, comprising administering to a patient in need thereof an effective amount of a compound having the following formula:
- ##STR5## wherein n is 2;
- Y is O or S;
- X is O, S or NH;
- and R is C.sub.1 -C.sub.18 alkyl or acyl which may be substituted;
- provided that in the treatment of allergic diseases, when Y is S and X is O, R is not acetyl.
A method for preventing transplant rejection, which comprises administering to a patient in need thereof an effective amount of a compound having the following formula:
- ##STR6## wherein n is 2;
- Y is O or S;
- X is O, S or NH;
- and R is C.sub.1 -C.sub.18 alkyl or acyl which may be substituted.
A method for treating a disease of a patient by suppressing the patient's immune system, comprising administering to a patient in need thereof an effective amount of a compound having the following formula:
- ##STR7## wherein n is 2;
- Y is O or S;
- X is O, S or NH;
- and R is C.sub.1 -C.sub.18 alkyl or acyl which may be substituted, provided that when Y is S and X is O, R is not acetyl.
Dependencies are inferred from the claim text.