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US 5,776,690 AGranted
Detection of chronic fatigue syndrome by decreased levels of RNase L inhibitor mRNA
OwnerAristo Vojdani, Eli Mordechaiinventors
Life of this patent
Estimating the term…
Abstract
Chronic fatigue syndrome in an individual is diagnosed by determining the level of RNase L inhibitor mRNA or protein in peripheral blood mononuclear cells. Significantly decreased levels of RLI mRNA or protein compared to healthy control individuals indicates the presence of chronic fatigue syndrome.
Claims4
A method for detecting an increased likelihood of the presence of chronic fatigue syndrome (CFS) in an individual, comprising:
- isolating peripheral blood mononuclear cells (PBMCs) from said individual;
- and
- determining the amount of RNase L inhibitor (RLI) mRNA present in said PBMCs from said individual, wherein the presence of an amount of RLI MRNA less than about 750copies/.mu.g RNA indicates an increased likelihood of the presence of CFS.
Dependencies are inferred from the claim text.