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US 5,776,434 AGranted
Medicinal aerosol formulations
AssigneeRiker Laboratories, Inc.
InventorsTarlochan S. Purewal, David J. Greenleaf
Life of this patent
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Abstract
A self-propelling aerosol formulation which may be free from CFC's which comprises a medicament, 1,1,1,2-tetrafluoroethane, a surface active agent and at least one compound having a higher polarity than 1,1,1,2-tetrafluoroethane.
Claims1
A method of making an aerosol formulation suitable for delivery to the lung by inhalation comprising the steps of:
- (a) providing an aerosol container, and
- (b) charging to said container:
- (i) a medicament in an amount sufficient to provide a plurality of therapeutically effective doses,
- (ii) an amount of propellant sufficient to propel from said container said plurality of therapeutically effective doses, said propellant being substantially free of chlorofluorocarbons and comprising 1,1,1,2-tetrafluoroethane;
- and
- (iii) at least one compound selected from the group consisting of ethyl alcohol, isopropyl alcohol, n-pentane, isopentane, neopentane, isopropyl myristate, and mixtures thereof, and
- (iv) a surface active agent.
4 more elements
Dependencies are inferred from the claim text.