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AssigneeThe Regents of the University of California
InventorsStephen Fuerstenau, W. Henry Benner, Norman Madden, William Searles
Estimating the term…
A mass spectrometer determines the mass of multiply charged high molecular weight molecules. This spectrometer utilizes an ion detector which is capable of simultaneously measuring the charge z and transit time of a single ion as it passes through the detector. From this transit time, the velocity of the single ion may then be derived, thus providing the mass-to-charge ratio m/z for a single ion which has been accelerated through a known potential. Given z and m/z, the mass m of the single ion can then be calculated. Electrospray ions with masses in excess of 1 MDa and charge numbers greater than 425 e.sup.- are readily detected. The on-axis single ion detection configuration enables a duty cycle of nearly 100% and extends the practical application of electrospray mass spectrometry to the analysis of very large molecules with relatively inexpensive instrumentation.
A mass spectrometer system for detecting the mass of large molecules comprising:
A mass spectrometer system for detecting large molecules comprising:
A mass spectrometer system for detecting large molecules comprising:
A mass spectrometer system for detecting large molecules and comprising:
A mass spectrometer system for detecting large molecules and comprising:
A method of analyzing the mass of large molecules utilizing a mass spectrometer system, comprising the steps of:
A mass spectrometer system for detecting large molecules comprising:
Dependencies are inferred from the claim text.