Recombinant heterodimeric human fertility hormones, and methods, cells, and vectors and DNA for the production thereof
AssigneeGenzyme Corporation
InventorsVermuri B. Reddy, Nancy Hsiung, Anton K. Beck, Edward George Bernstine
Life of this patent
Estimating the term…
Abstract
Biologically active heterodimeric human fertility hormones composed of two different subunits, each subunit being synthesized in the same cell transformed by at least one cell expression vector having heterologous DNA encoding each subunit with each subunit being controlled by a separate promoter. Preferred human fertility hormones include hCG, hLH and hFSH.
Claims4
A recombinantly produced biologically active heterodimeric human fertility hormone selected from the group consisting of human chorionic gonadotropin, human luteinizing hormone, and human follicle stimulating hormone, free from contamination by any other proteins of human origin.
Dependencies are inferred from the claim text.