Use of sulfated saccharides to treat baldness
OwnerDaniel Bar-Shalom, Niels Bukhinventors
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Abstract
A method of treating and/or preventing alopecia (baldness, deficient hair growth) comprises administering to a patient in need thereof a therapeutically or prophylactically effective amount of a sulfated mono-, di- or oligosaccharide or a derivative, salt or complex thereof. The saccharide is preferably polysulfated, such as a polysulfated disaccharide, in particular sucrose, or a derivative, complex or salt thereof. Especially interesting polusulfated disaccharides are sucrose pentasulfate, sucrose hexasulfate, sucrose heptasulfate and sucrose octasulfate, e.g. in the form of a potassium or sodium salt, or in the form of sucralfate.
Claims23
A method of treating alopecia comprising topically administering to a patient in need thereof a therapeutically effective amount of a non-esterified compound effective against alopecia selected from the group consisting of i) non-esterified, sulfated monosaccharides, ii) non-esterified, sulfated disaccharides and iii) salts and complexes of (i) or (ii) above with a substance selected from the group consisting of alkali metals, alkaline earth metals, Al, Zn, Cu, Zr, Ti, Bi, Mn and Os.
A method of inhibiting the onset of alopecia, the method comprising topically administering to a patient in need thereof an inhibitory amount of a non-esterified compound effective against alopecia selected from the group consisting of i) non-estrified sulfated monosaccharides, ii) non-esterified sulfated disaccharides and iii) salts and complexes of i) or ii) above with a substance selected from the group consisting of alkali metals, alkaline earth metals, Al, Zn, Cu, Zr, Ti, Bi, Mn and Os.
A method of inhibiting loss of the natural color of hair, the method comprising topically administering to a patient in need thereof a cosmetically effective amount of a compound selected from the group consisting of i) sulfated monosaccharides, ii) sulfated disaccharides, iii) ester derivatives of said mono- and disaccharides, and iv) salts and complexes of said mono- and disaccharides with a substance selected from the group consisting of alkali metals, alkaline earth metals, Al, Zn, Cu, Zr, Ti, Bi, Mn and Os.
Dependencies are inferred from the claim text.