Tissue graft and method for urinary tract urothelium reconstruction and replacement
AssigneesPurdue Research Foundation, Methodist Hospital of Indiana, Inc.
InventorsPeter M. Knapp, Jr., James E. Lingeman, Robert J. Demeter, Stephen F. Badylak
Life of this patent
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Abstract
A method for surgical repair of a diseased or damaged bladder is described. Diseased or damaged bladder tissue is surgically replaced with submucosal tissue of a warm blooded vertebrate to promote regrowth of endogenous urinary bladder tissue.
Claims8
A tissue graft construct for replacement of damaged or diseased portions of a urinary bladder, said construct comprising a sheet of submucosal tissue of a warm-blooded vertebrate formed as a pouch having ports for surgical attachment and fluid communication with the ureters and the urethra for replacement of 20% or more of the urinary bladder.
A tissue graft construct for replacement of damaged or diseased portions of a urinary bladder, said construct comprising submucosal tissue of a warm-blooded vertebrate formed as a pouch for replacement of 70% or more of the urinary bladder.
A tissue graft construct for the replacement of a urinary bladder, said construct comprising submucosal tissue of a warm-blooded vertebrate in the shape of a pouch for replacement of the entire urinary bladder, said pouch having ports for surgical attachment and fluid communication with the ureters and the urethra.
Dependencies are inferred from the claim text.