Method for treating mastitis and other staphylococcal infections
AssigneeAMBI Inc.
InventorsPeter Blackburn, June Polak
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Abstract
Lysostaphin is used to eliminate and cure staphylococcal infections including the cure of mastitis by intramammary infusion. Administration of from 2 mg to 400 mg of lysostaphin to an infected bovine mammary gland eliminates staphylococci, and the reoccurrence common with antibiotic therapy is not observed. Teat-dips containing lysostaphin, mutanolysin and lysozyme can be used as a prophylactic. Synergistic enhancement of the killing effect of lysostaphin is observed when a mild surfactant or penicillin or both is included in the formulation.
Claims5
A method of treating recurring staphylococcal mastitis resulting from intracellular Staphylococcus aureus comprising administering to an infected gland by intramammary infusion a therapeutic agent consisting essentially of the bacteriocin lysostaphin produced by recombinant means in a pharmaceutically acceptable carrier in an amount effective to eliminate the recurring staphylococcal mastitis.
Dependencies are inferred from the claim text.