Methods of treating disease using sertoli cells and allografts or xenografts
AssigneeResearch Corporation Technologies, Inc.
InventorHelena P. Selawry
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Abstract
The present invention describes a method of treating a disease that results from a deficiency of a biological factor which comprises administering to a mammal Sertoli cells and cells that produce the biological factor. In particular, the present invention describes a method of treating diabetes mellitus by transplanting pancreatic islet of Langerhans cells in conjunction with Sertoli cells to create an immunologically privileged site. A method of creating an immunologically privileged site in a mammal for cellular transplants is further described by the present invention. A pharmaceutical composition comprising Sertoli cells and cells that produce a biological factor is also provided.
Claims6
A pharmaceutical composition comprising Sertoli cells and cells that produce a biological factor and a pharmaceutically acceptable carrier.
A pharmaceutical composition comprising Sertoli cells, pancreatic islet of Langerhans cells and a pharmaceutically acceptable carrier.
A pharmaceutical composition comprising Sertoli cells and a pharmaceutically acceptable carrier.
Dependencies are inferred from the claim text.