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US 5,756,687 AGranted
Isolation of components of interest from milk
AssigneeGenzyme Transgenics Corporation
InventorsJulie S. Denman, Edward S. Cole
Life of this patent
Estimating the term…
Abstract
Methods of isolating components of interest from a milk sample are described. The methods include a step wherein the solubility of at least a portion of the total milk protein is stabilized in such a manner as to allow isolation of the component of interest without significant loss in yield. Kits for stabilizing the solubility of at least a portion of the total milk protein of the milk sample containing the component of interest also are described.
Claims16
A method of isolating a protein of intrest from a milk sample, comprising:
- contacting a milk sample containing a protein of interest with a cationic solubilizing agent under conditions which stabilize the solubility of at least a portion of the total milk protein such that the protein of interest can be isolated from the solubilized milk sample with less than 50% loss of the protein of interest;
- and
- isolating the protein of interest from the solubilized milk sample in a form which is biologically active.
Dependencies are inferred from the claim text.