Pulverulent hydroxypropyl-.beta.-cyclodextrin composition and process for its preparation
AssigneeRoquette Freres
InventorsPatrick Fuertes, Bruno Vappereau, Michel Serpelloni, Jose Lis
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Abstract
The invention relates to a novel pulverulent hydroxypropyl-.beta.-cyclodextrin compound having a centered particle size free of fine particles and an appreciably improved capacity to dissolve in aqueous medium. The compound also has good flowability and has the advantage of being compressible. The invention also relates to a process for the preparation of this pulverulent hydroxypropyl-.beta.-cyclodextrin compound.
Claims13
Pulverulent hydroxypropyl-.beta.-cyclodextrin compound, containing less than about 25% of particles smaller than 100 microns in size and having a dissolution time in aqueous medium, measured according to a Test I, of less than 5 minutes at 21.degree. C. for a solution with a solids content of 20% by weight, said Test I consisting of introducing a solution of the HP.beta.CD into a tall beaker, stirring the solution at 1250 revolutions/minute until perfect visual clarity of the solution is reached.
Dependencies are inferred from the claim text.