Derivatives of 4-hydroxybutyric acid
OwnerGernot Koehler, Anita Koehlerinventors
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Abstract
The invention describes new salts and amides of 4-hydroxybutyric acid with the aim of improving the pharmacological and therapeutic properties of 4-hydroxybutyric acid.
Claims5
A parenteral preparation for narcosis in anaesthesia consisting essentially of an aqueous solution of at least one compound selected from the group consisting of N-2-hydroxyethyl-4-hydroxybutyramide, N-2-hydroxyethyl-N-methyl-4-hydroxybutyramide, N,N-bis-(2-hydroxyethyl)-4-hydroxybutyramide and N-(1-hydroxymethyl-2-hydroxyethyl)-4-hydroxybutyramide.
A parenteral preparation for sleep induction or long-term sedation consisting essentially of an aqueous solution of at least one compound selected from the group consisting of N-2-hydroxyethyl-4-hydroxybutyramide, N-2-hydroxyethyl-N-methyl-4-hydroxyb utyramide, N,N-bis-(2-hydroxyethyl)-4-hydroxybutyramide and N-(1-hydroxymethyl-2-hydroxyethyl)-4-hydroxybutyramide.
An oral preparation for alcohol withdrawal therapy consisting essentially of at least one compound selected from the group consisting of N-2-hydroxyethyl-4-hydroxybutyramide, N-2-hydroxyethyl-N-methyl-4-hydroxybutyramide, N,N-bis-(2-hydroxyethyl)-4-hydroxybutyramide and N-(1-hydroxymethyl-2-hydroxyethyl)-4-hydroxybutyramide and a pharmaceutically effective carrier.
An oral preparation for therapy of cataplexy or narcolepsy consisting essentially of at least one compound selected from the group consisting of N-2-hydroxyethyl-4-hydroxybutyramide, N-2-hydroxyethyl-N-methyl-4-hydroxybutyramide, N,N-bis-(2-hydroxyethyl)-4-hydroxybutyramide and N-(1-hydroxymethyl-2-hydroxyethyl)-4-hydroxybutyramide and a pharmaceutically effective carrier.
An oral preparation for therapy of sleep disturbance syndrome consisting essentially of comprising at least one compound selected from the group consisting of N-2-hydroxyethyl-4-hydroxybutyramide, N-2-hydroxyethyl-N-methyl-4-hydroxybutyramide, N,N-bis-(2-hydroxyethyl)-4-hydroxybutyramide and N-(1-hydroxymethyl-2-hydroxyethyl)-4-hydroxybutyramide and a pharmaceutically effective carrier.
Dependencies are inferred from the claim text.