Method for enhancing functional properties of submucosal tissue graft constructs
AssigneePurdue Research Foundation
InventorsStephen F. Badylak, Sherry Voytik
Life of this patent
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Abstract
A tissue graft construct comprising submucosal tissue of a warm-blooded vertebrate and a proliferating population of cells is described. The submucosal graft constructs used in accordance with the present invention induce host tissue proliferation, remodeling and regeneration of appropriate tissue structures upon implantation in a host.
Claims6
A method for enhancing the capabilities of a submucosal tissue graft construct to repair damaged or diseased tissue, said method comprising the step of seeding the submucosal tissue with cells selected from the group consisting of endothelial cells, keratinocytes and mesenchymal cells prior to implanting or injecting the graft construct into a host.
Dependencies are inferred from the claim text.