Injectable or implantable biomaterials for filling or blocking lumens and voids of the body

A method for completely or partially blocking, augmenting, sealing, or filling a biological lumen or void within the body of a patient comprising administering an effective amount of a biomaterial into the lumen or void;

• wherein the biomaterial is crosslinked using a mixture of hydrophilic and hydrophobic crosslinking agents.

A method for completely or partially blocking, augmenting, sealing, or filling a biological lumen or void within the body of a patient comprising administering an effective amount of a biomaterial into the lumen or void;

• wherein the biomaterial is a polymeric hydrogel which comprises a first synthetic polymer crosslinked using a second synthetic polymer, wherein the first synthetic polymer contains two or more nucleophilic groups, and the second synthetic polymer contains two or more electrophilic groups capable of forming covalent bonds with the nucleophilic groups on the first synthetic polymer.