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US 5,747,462 AGranted
Pharmaceutically active compounds and their use
AssigneeLaboratorio CHile S.A.
InventorVictoria M. Fuentes
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AssigneeLaboratorio CHile S.A.
InventorVictoria M. Fuentes
Estimating the term…
The present invention relates to the area of pharmacology; its objective is to solve the technical problem of inflammation, pain, pruritus and local hyperthermia in human beings and animal species. The composition and the subcompositions thereof are obtained from plants of the family Cactaceae, the main methodological steps being a set of processes: production, purification, physicochemical quantification, biotherapeutic evaluation, biopharmaceutical formulation and molecular identification. From the molecular identification a set of molecules is recognized, comprising carbohydrates and an aromatic amine, the general formulae of which are: C.sub.5 H.sub.10 O.sub.5 (RIBOSE), C.sub.6 H.sub.12 O.sub.5 (FUCOSE), C.sub.6 H.sub.12 O.sub.6 (GALACTOSE; MANNOSE; GLUCOSE), C.sub.8 H.sub.11 O.sub.2 N (1-HYDROXY-1-(4-HYDROXYPHENYL)-2-AMINOETHANE), C.sub.10 H.sub.18 O.sub.9 (RIBOFURANOSYLRIBOSE).
A composition derived from a plant of the Cactaceae family, said composition consists essentially of a mixture of:
The method of 3 wherein the mode of administration is selected from a group consisting of enteral, parenteral, dermal, ocular, nasal, otic, rectal, vaginal, urethral, buccal and pharyngotracheobronchial routes.
A composition derived from a plant of the Cactaceae family, said consists essentially of a mixture of an aromatic amine of formula (R,S)-1-hydroxy-1-(-4-hydroxy-phenyl-)-2-amino-ethane and one or more structural isomers of monosaccharides of galactose and mannose, wherein said monosaccharide is in any one of:
A composition derived from a plant of the Cactaceae family, said consists essentially of a mixture of a disaccharide of formula n1-O-(.alpha.,.beta.)-(D,L)-ribofuranosyl-(w.alpha.,.beta.)-(D,L)-ribofura nose and at least one structural isomers of monosaccharide of ribose, wherein said monosaccharide is in any one of:
A composition derived from a plant of the Cactaceae family, said consists essentially of a mixture of at least one structural isomer of monosaccharide of glucose, wherein said monosaccharide is in any one of:
A composition derived from a plant of the Cactaceae family, said consists of a mixture of at least one structural isomer of monosaccharide of fucose, wherein said monosaccharide is in any one of:
Dependencies are inferred from the claim text.