Targeted co-polymers for radiographic imaging
AssigneeThe General Hospital Corporation
InventorsVladimir P. Torchilin, Vladimir S. Trubetskoy, Gerald L. Wolf, G. Scott Gazelle
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Abstract
A radiographic imaging agent including a plurality of block copolymers forming a micelle, the block copolymers including a hydrophilic polymer linked to a hydrophobic polymer, and the hydrophobic polymer including a backbone incorporating radiopaque molecules via covalent bonds.
Claims23
A targeted compound capable of forming micelles in an aqueous solution, said compound comprising a hydrophilic polymer linked to a hydrophobic polymer, and a targeting ligand linked to one of said hydrophilic polymer or said hydrophobic polymer, wherein said hydrophobic polymer comprises a backbone incorporating radiopaque molecules via covalent bonds.
A targeted radiographic imaging agent comprising a plurality of block copolymers forming a micelle and a targeting ligand linked to said block copolymers, said block copolymers comprising a hydrophilic polymer linked to a hydrophobic polymer, and said hydrophobic polymer comprising a backbone incorporating radiopaque molecules via covalent bonds.
Dependencies are inferred from the claim text.