Stent for liberating drug
OwnerKeiji Igaki, Hideo Tamaiinventors
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Abstract
A stent according to the present invention is adapted to be introduced into a vascular system such as blood vessels. The stent includes a stent body produced by weaving or knitting a fiber containing a drug and made of a low-melting biodegradable polymer into a tubular shape, or coating a drug-containing low-melting biodegradable polymer on a stent body. When the stent is introduced into the vascular system, the drug contained therein is dosed in a locally limited region of the vascular system. The low-melting biodegradable polymer used has a melting point of 80.degree. C. or lower and is at least one compound selected from the group consisting of poly-.epsilon.-caprolactone, poly-D, L-deca-lactone, poly-dioxane and a copolymer thereof.
Claims3
A stent for liberating TRANIRAST, which is adapted to be introduced into a vascular system such as blood vessels, comprising a stent body produced by weaving or knitting into a tubular shape a fiber containing TRANIRAST and made of a low-melting biodegradable polymer having a melting point at which no pharmacological effects of TRANIRAST are damaged.
A stent for eluting TRANIRAST contained therein, comprising a stent body coated with a mixture composed of TRANIRAST and a low-melting biodegradable polymer having a melting point at which no pharmacological effects of TRANIRAST are damaged.
A stent for liberating a drug, which is adapted to be introduced into a vascular system such as blood vessels, comprising:
- a stent body produced by weaving or knitting into a tubular shape a composite fiber composed of fiber made of a low-melting biodegradable polymer having a melting point at which no pharmacological effects of the druq are damaged and a fiber made of a high-melting biodegradable polymer having a melting point higher than that of the fiber composed of the low-melting biodegradable polymer;
- wherein the low-melting biodegradable polymer exposed to an outer surface of the stent body is heat-fused to smoothen the outer surface;
- wherein the high-melting biodegradable polymer is at least compound selected from the group consisting of poly-lactic acid, polyglycolic acid and a copolymer thereof;
- wherein the melting point of the low-melting point biodegradable polymer is 80.degree. C. or lower;
- and
- wherein the composite fiber constituting the stent body is a two folded yarn, the two folded yarn including a TRANIRAST-containing poly-.epsilon.-caprolactone fiber.
Dependencies are inferred from the claim text.