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US 5,728,719 AGranted
Systemic control of parasites
AssigneeVirbac
InventorThomas A. Miller
Life of this patent
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AssigneeVirbac
InventorThomas A. Miller
Estimating the term…
The present invention is a method for controlling ectoparasites. More particularly, the invention relates to a method of treatment in which the warm blooded animal is dosed with an ovicidally effective amount of a heterocyclic nitrogen compound selected from the group represented by the formula: ##STR1## wherein R.sub.1, is either one of the following groups: ##STR2## in which R.sub.7, R.sub.8, R.sub.9, R.sub.10, R.sub.11, R.sub.12, R.sub.13, R.sub.14, R.sub.15, R.sub.16, and R.sub.17 are, the same or different, each a hydrogen atom, a halogen atom, a C.sub.1 -C.sub.4 alkoxy group, a C.sub.1 -C.sub.4 alkylthio group, a trifluoro methyl group or a vitro group, R.sub.18, R.sub.19, R.sub.20 and R.sub.21 are, the same or different, each a hydrogen atom or a methyl group, k is an integer of 0 to 1 and 1 is an integer of 0 to 3; R.sub.2 and R.sub.3 are, the same or different, each a hydrogen atom, a halogen atom or a methyl group; R.sub.4 is a halogen atom or a methyl group; R.sub.5 and R.sub.6 are, the same or different, each a hydrogen atom, a halogen atom, a C.sub.1 -C.sub.4 haloalkyl group or a C.sub.1 -C.sub.4 haloalkoxy group; X, Y and Z are, the same or different, each an oxygen atom, a sulfur atom or a methylene group, m is an integer of 0 to 4, and n is an integer of 0 to 2, which is transmitted to the ectoparasite by the animal's blood. In a further embodiment, a compound selected from the group consisting of ivermectin, milbemycin, milbemycin oxime, moxidectin and avermectin and avermectin derivatives.
A composition comprising a pharmaceutically acceptable carrier for veterinary use, the composition being formulated to deliver an amount in the range of 0.001 mg to 1000 mg of compound per kilogram of animal body weight to produce when administered to a host animal an ovicidally effective amount of a compound having the formula:
A dietary supplement composition comprising a pharmaceutically acceptable carrier for veterinary use formulated to deliver an amount in the range of 0.001 mg to 1000 mg of compound per kilogram of animal body weight to produce when administered to a host animal in the host animal's blood an ovicidally effective amount of a compound having the formula:
A composition comprising pyriproxifen formulated to deliver a sufficient amount of pyriproxifen to the blood of a host animal to provide an ovicidally effective concentration to an ectoparasite feeding on the blood of the animal.
A composition formulated as a single dose in the range of about 10 to 200 mg/kg of 2-1-methyl-2-(4-phenoxyphenoxy)ethoxy!pyridine (pyriproxifen) with a pharmaceutically acceptable carrier chosen to deliver an ovicidally effective amount to the animal's blood stream for at least 25 days.
Dependencies are inferred from the claim text.