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US 5,726,292 AGranted
Immuno-potentiating systems for preparation of immunogenic materials
OwnerGeorge H. Lowellinventor
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Abstract
The invention is directed to improved immunopotentiating systems for preparation of immunogenic materials. More particularly, the invention is directed to immunogenic compositions containing a protein, polypeptide, or peptide, a hydrophobic anchor, and a proteosome. The immunogenic compositions are suitable for use as therapeutic agents and vaccines.
Claims15
A construct comprising:
- (1) a protein, protein fragment, polypeptide or peptide,
- (2) a hydrophobic anchor, and
- (3) a proteosome.
A method of step 9 wherein the product of step (2) is complexed with the proteosome by dialysis.
A construct comprising:
- (1) a protein, polypeptide or peptide,
- (2) a hydrophobic anchor, said anchor being a peptide of formula
- Gly Gly Tyr Cys Phe Val Ala Leu Leu Phe (SEQ ID NO:
- 11), and
- (3) a proteosome.
2 more elements
Dependencies are inferred from the claim text.