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US 5,723,305 AGranted
Marker for male infertility and/or fertility
OwnerRobert Sullivan, Franck Boueinventors
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Abstract
The present invention relates to a method for the diagnosis of male infertility which comprises the steps of a) determining the amount of P34H in a sperm sample; and b) comparing the determined amount of step (a) with a fertile control sample. The present invention also relates to a kit for the diagnosis of male infertility which comprises an anti-P34H antibody enzyme-labeled, an enzyme substrate and a fertile control sample.
Claims2
A method for the diagnosis of male infertility which comprises the steps of:
- a) determining the amount of P34H, a 34 kDa human epididymal sperm protein, in a sperm sample using an antibody specific to P34H;
- and
- b) comparing the determined amount of step a) with a fertile control sample, wherein a P34H value lower than 30% of the fertile control sample is indicative of infertility.
A kit for the diagnosis of male infertility which comprises:
- a) an anti-P34H antibody enzyme-labeled;
- b) an enzyme substrate;
- and
- c) a fertile control sample.
1 more element
Dependencies are inferred from the claim text.