Back to results
US 5,721,243 AGranted
Radiopharmaceutical agents for the detection of Alzheimers disease
AssigneeRegents of the University of Minnesota
InventorsSimon Mbua Ngale Efange, Stanley M. Parsons
Life of this patent
Estimating the term…
Abstract
Novel anticholinergics which are related to vesamicol are particularly useful when radiolabeled for evaluating cholinergic innervation in the living human brain. The cholinergic deficit in the Alzheimer's brain should be identifiable with these radioligands.
Claims2
An anticholinergic composition comprising a chemical with the structural formula:
- ##STR4## wherein X is CH, N;
- Y is a phenyl group;
- Z is H, or a phenyl, naphthyl, thiophene or pyrrol group;
- W is H, or a phenyl, naphthyl, thiophene or pyrrol group;
- and
- further characterized in that both Z and W cannot be H.
3 more elements
An anticholinergic composition comprising a chemical with the structural formula:
- ##STR5## wherein X is CH, N;
- m is 0 to 5;
- n is 0 to 3;
- Y is a phenyl group;
- Z is H, or a phenyl, naphthyl, thiophene or pyrrol group;
- W is H, or a phenyl, naphthyl, thiophene or pyrrol group;
- and
- further characterized in that both Z and W cannot be H.
5 more elements
Dependencies are inferred from the claim text.